PowerHouse Complex

Written By Cody Strodtman

Our Cellular Health Formula

PowerHouse Complex is packed with scientifically-proven ingredients to help you Reach Your Peak.

PowerHouse Complex is expertly formulated to support the mitochondria, cellular health and optimize overall well-being by protecting cells from oxidative stress. Third-party tested and certified for safety. Our proprietary blend PowerHouse Complex combines powerful antioxidants that boost METABOLISM, HEART, and BRAIN HEALTH. Alpha-Lipoic Acid (ALA), Pyrroloquinoline Quinone (PQQ), Coenzyme Q10 (CoQ10), and L-Ergothioneine—work together to support optimal health.

L-Ergothioneine has an ultra-long half-life (days to weeks!), keeping your cells resilient! L-ergo is a unique antioxidant with diverse health advantages:
- Antioxidant Properties: L-Ergothioneine acts as a potent antioxidant, protecting cells from oxidative stress and reducing inflammation.
- Metabolic Health: Supplementation with L-Ergothioneine has been shown to improve metabolic profiles in individuals with metabolic syndrome, potentially aiding in the management of this condition.
- Mitochondrial Function: L-Ergothioneine may help preserve mitochondrial function by increasing antioxidant levels and reducing inflammatory responses associated with many chronic health conditions.

Pyrroloquinoline Quinone (PQQ) stays active 3-5 days, powering mitochondria for the long run! PQQ is a powerful compound that supports various aspects of health:
- Mitochondrial Health: PQQ enhances mitochondrial function, leading to increased energy production and improved metabolism.
- Neuroprotection: Research indicates that PQQ has neuroprotective properties, potentially improving cognitive functions such as attention, memory, and information processing.
- Metabolic Health: PQQ has been shown to improve metabolic health by reducing visceral and liver fat accumulation, promoting better overall metabolic function.
- Longevity Support: PQQ has been associated with increased lifespan in certain models, potentially due to its role in cellular energy production and antioxidant defense mechanisms.
- Immune System Enhancement: Research indicates that PQQ can improve immune responsiveness, aiding the body's defense against various pathogens.

Alpha Lipoic Acid (ALA) is fast-acting with a short half-life (30 min - 1 hr) for quick antioxidant support! ALA is a powerful antioxidant that offers numerous health benefits:
- Antioxidant Powerhouse: ALA neutralizes free radicals, protecting cells from oxidative damage and supporting overall health.
- Blood Sugar Support: ALA enhances insulin sensitivity and helps regulate blood sugar levels, benefiting individuals with type 2 diabetes.
- Nerve Health: ALA reduces symptoms of peripheral neuropathy, such as tingling and nerve pain, by combating free radicals that cause nerve damage.

Coenzyme Q10 (CoQ10) is long-lasting with a half-life of 33-35 hours, fueling your cells all day! CoQ10 offers a range of health benefits beyond heart health, migraine relief, and blood pressure regulation:
- Fatigue Reduction: CoQ10 supplementation has been shown to alleviate symptoms of fatigue in various conditions, including chronic fatigue syndrome and fibromyalgia.
- Antioxidant Defense: CoQ10 plays a crucial role in reducing lipid peroxidation and protecting blood vessels by preserving nitric oxide, thereby enhancing overall vascular health.
- Blood Sugar Regulation: Research suggests that CoQ10 may help improve blood sugar control, which is beneficial for individuals managing diabetes.

These antioxidants are naturally found in foods like mushrooms, green tea, red meat, organ meats, and certain fruits and vegetables.To maximize their benefits, consider supplementing with ALA, PQQ, CoQ10, and L-Ergothioneine to support overall health!

References:

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  2. Jonscher KR, Chowanadisai W, Rucker RB. Pyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention. Biomolecules. 2021 Sep 30;11(10):1441. doi: 10.3390/biom11101441

  3. Maglione E, Marrese C, Migliaro E, Marcuccio F, Panico C, Salvati C, Citro G, Quercio M, Roncagliolo F, Torello C, Brufani M. Increasing bioavailability of (R)-alpha-lipoic acid to boost antioxidant activity in the treatment of neuropathic pain. Acta Biomed. 2015 Dec 14;86(3):226-33

  4. Morillon AC, Williamson RD, Baker PN, Kell DB, Kenny LC, English JA, McCarthy FP, McCarthy C. Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia. PLoS One. 2020 Mar 31;15(3):e0230977. doi: 10.1371/journal.pone.0230977

  5. Nguyen H, Pellegrini MV, Gupta V. Alpha-Lipoic Acid. 2024 Jan 26. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan

  6. Paul BD. Ergothioneine: A Stress Vitamin with Antiaging, Vascular, and Neuroprotective Roles? Antioxid Redox Signal. 2022 Jun;36(16-18):1306-1317. doi: 10.1089/ars.2021.0043

  7. Petca A, Rusu C, Bratu T, et al. Benefits of α-lipoic acid in high-risk pregnancies (Review). Exp Ther Med. 2021;22(5):1232. doi:10.3892/etm.2021.10666

  8. Superti F, Russo R. Alpha-lipoic acid: Biological mechanisms and health benefits. Antioxidants (Basel). 2024;13(10):1228. doi:10.3390/antiox13101228

  9. Samimi F, Mozaffari M, Tabrizian H, et al. Coenzyme Q10: A key antioxidant in the management of diabetes-induced cardiovascular complications—An overview of mechanisms and clinical evidence. Int J Endocrinol. 2024;2024:2247748. doi:10.1155/2024/2247748

  10. Sood B, Patel P, Keenaghan M. Coenzyme Q10. 2024 Jan 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan

  11. Tamakoshi M, Suzuki T, Nishihara E, Nakamura S, Ikemoto K. Pyrroloquinoline quinone disodium salt improves brain function in both younger and older adults. Food Funct. 2023 Mar 6;14(5):2496-2501. doi: 10.1039/d2fo01515c

  12. Testai L, Martelli A, Flori L, Cicero AFG, Colletti A. Coenzyme Q10: Clinical Applications beyond Cardiovascular Diseases. Nutrients. 2021 May 17;13(5):1697. doi: 10.3390/nu13051697

  13. Tian X, Sun J, Zhang Y, et al. Ergothioneine: An underrecognised dietary micronutrient required for healthy ageing? Br J Nutr. 2023;129(1):104-114. doi:10.1017/S0007114522003592

  14. Tian X, Cioccoloni G, Sier JH, Naseem KM, Thorne JL, Moore JB. Ergothioneine supplementation in people with metabolic syndrome (ErgMS): protocol for a randomised, double-blind, placebo-controlled pilot study. Pilot Feasibility Stud. 2021 Oct 29;7(1):193. doi: 10.1186/s40814-021-00929-6

Cody Strodtman
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